Alexander DeLuca, M.D.
Addiction, Pain, & Public Health website

[Home] [Library]  [Slides]  [Search]  [Medline]  [Links]

[Statements of Purpose, Ownership, Sponsorship. Privacy,  Email Confidentiality, and Advertising Policies.]

Decreased Depression in Marijuana Users
[Abstract, References, and Link to Full Text PDF]

by Thomas F. Densona and Mitchell Earleywine; Addictive Behavior; 2005; Posted: 2005-11-30; Modified: 2007-10-24.



 [Related resources =]
See also:
THE WAR ON PAIN SUFFERERS #3 - Medical Marijuana archives

Antidepressant-Like Activity and Modulation of Brain Monoaminergic Transmission by Blockade of Anandamide Hydrolysis - G. Gobbi, et al.; 2005

Add to       Add to Technorati Faves      Add to Stumbleupon       Add to Netvouz      Add to Digg

[FULL TEXT of this Article in Adobe PDF format]


Over 4400 adult internet users completed The Center for Epidemiologic Studies Depression scale and measures of marijuana use. We employed an internet survey in an effort to recruit the most depressed and marijuana-involved participants, including those who might prove unwilling to travel to the laboratory or discuss drug use on the phone or in person. We compared those who consumed marijuana daily, once a week or less, or never in their lives. Despite comparable ranges of scores on all depression subscales, those who used once per week or less had less depressed mood, more positive affect, and fewer somatic complaints than non-users. Daily users reported less depressed mood and more positive affect than non-users. The three groups did not differ on interpersonal symptoms. Separate analyses for medical vs. recreational users demonstrated that medical users reported more depressed mood and more somatic complaints than recreational users, suggesting that medical conditions clearly contribute to depression scores and should be considered in studies of marijuana and depression. These data suggest that adults apparently do not increase their risk for depression by using marijuana.


Degenhardt et al., 2003 L. Degenhardt, W. Hall and M. Lynskey, Exploring the association between cannabis use and depression, Addiction 98 (2003), pp. 14931504.

Fergusson & Horwood, 1997 D. Fergusson and L. Horwood, Early onset cannabis use and psychosocial adjustment in young adults, Addiction 92 (1997), pp. 279296. Abstract-EMBASE | Abstract-PsycINFO | Abstract-MEDLINE

Fergusson et al., 1996 D. Fergusson, M. Lynskey and L. Horwood, The short-term consequences of early onset cannabis use, Journal of Abnormal Child Psychology 24 (1996), pp. 499512. Abstract-MEDLINE | Abstract-PsycINFO | Full Text via CrossRef

Green & Ritter, 2000 B.E. Green and C. Ritter, Marijuana use and depression, Journal of Health and Social Behavior 41 (2000), pp. 4049. Abstract-PsycINFO | Abstract-MEDLINE

Kouri et al., 1995 E. Kouri, H. Pope, D. Yurgelun-Todd and S. Gruber, Attributes of heavy vs. occasional marijuana smokers in a college population, Biological Psychiatry 38 (1995), pp. 475481. Abstract | PDF (570 K)

McGee et al., 2000 R. McGee, S.A. Williams, R. Poulton and T. Moffitt, A longitudinal study of cannabis use and mental health from adolescence to early adulthood, Addiction 95 (2000), pp. 491503. Abstract-MEDLINE | Abstract-PsycINFO | Abstract-EMBASE

Musty & Kaback, 1995 R.E. Musty and L. Kaback, Relationships between motivation and depression in chronic marijuana users, Life Sciences 56 (1995), pp. 21512158. SummaryPlus | Full Text + Links | PDF (637 K)

Radloff, 1977 L.S. Radloff, The CES-D scale: A self-report depression scale for research in the general population, Applied Psychological Measurement 1 (1977), pp. 385401. Abstract-PsycINFO

Rom, 1990 D.M. Rom, A sequentially rejective test procedure based on a modified Bonferroni inequality, Biometrika 77 (1990), pp. 663666.

Rowe et al., 1995 M.G. Rowe, M.F. Fleming, K. Barry, L.B. Manwell and S. Kropp, Correlates of depression in primary care, Journal of Family Practice 41 (1995), pp. 551558. Abstract-EMBASE | Abstract-MEDLINE | Abstract-PsycINFO

Wilcox, 2003 R.R. Wilcox, Applying contemporary statistical techniques, Elsevier, San Diego (2003).

[FULL TEXT of this Article in Adobe PDF format]



Dr. DeLuca's Addiction, Pain, and Public Health Website

Alexander DeLuca, M.D.

[Top of Page]

Originally posted: 2005-11-30

All Email to: 

Statements of Purpose, Ownership, Sponsorship. Privacy,  Email Confidentiality, and Advertising Policies

Most recently revised: 2007-10-24
Copyright: Creative Commons 2007

Creative Commons License Licensed under a Creative Commons Attribution-NoDerivs 2.5 License.        We subscribe to the HONcode principles of the HON Foundation. Click to